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              厄貝沙坦

              基本信息
              化學名稱:
              2-丁基-3-[4-[2-(1H-四唑-5-基)苯基]芐基]-1,3-二氮雜螺-[4,4]壬-1-烯-4-酮;
              結構式:

                   

              分子式:C25H28N6O
              分子量:428.54
              CAS號:138402-11-6
              質量標準:USP/ EP/ 國家標準, GMP/ DMF 可用。

                 Specification

                USP 36

                   Items

                Specification

               Test results

                   Appearance

                White to almost white crystalline powder

                White crystalline powder

                   Identification

                IR: Should comply with reference standard

                 Complies

              HPLC: Should comply with reference standard

                 Complies

                   Water

                 NMT 0.5%

                 0.15%

                   Sulphated ash

                 NMT 0.2%

                 NMT 0.2%

                   Heavy meatals

                 NMT 0.002%

                 NMT0.002%

                   Limit of Azide

                 NMT 10ppm

                 NMT 10ppm

                   Related compounds A

                 NMT 0.2%

                 0.002%

               Any other individual impurity

                 NMT 0.1%

                 0.004%

                   Total impurities

                  (excluding R-isomer)

                 NMT 0.5%

                 0.15%

                  Residual solvents

                 Ethanol: NMT 5000 ppm

                 28ppm

                 Dichloromethane: NMT600 ppm

                Not detected

                 D, D-dimethylformamide NMT880 ppm

                Not detected

                 t-butyl methyl ether NMT5000 ppm

                Not detected

                 Xylene: NMT1500ppm

                 320ppm

                 Toluene: NMT890ppm

                 Not detected

                   Assay (HPLC)

                 98.0~102.0%

                 99.9%

                   Conclusion

                 It Complies with USP36

               作用與用途: 抗高血壓,用于治療高血壓病
               
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